| GOLEADORES CAMPEONATO NACIONAL 2021 | ||
| Goles | Jugador | Equipo |
| 21 | Maximiliano Silvera | Cerrito |
| 15 | Gonzalo Bergessio | Nacional |
| 15 | Douglas Matias Arezo | River Plate |
| 14 | Leandro Otormin | Cerro Largo |
| 14 | Federico Martinez | Liverpool |
| 13 | Agustin Alvarez Martinez | Peñarol |
| 11 | Juan Ignacio Ramirez | Liverpool |
| 10 | Ederson Salomon Rodriguez | Rentistas |
| 10 | Sebastian Guerrero | Torque |
| 9 | Lucas di Yorio | Cerro Largo |
| 9 | Lucas Rodriguez | Torque |
| 9 | Renzo Lopez | Wanderers-Plaza Colonia |
| 8 | Facundo Labandeira | Boston River |
| 8 | Mauren Franco | Fenix |
| 8 | Sebastian Fernandez | Liverpool |
| 8 | Pablo Ceppelini | Peñarol |
| 8 | Tomas Andrade | Sud America |
| 7 | Facundo Rodriguez | Boston River |
| 7 | Leandro Fernandez | Nacional |
| 7 | Ruben Bentancourt | Peñarol-Boston River |
| 7 | Thiago Borbas | River Plate |
| 6 | Facundo Torres | Peñarol |
| 6 | Diogo | Plaza Colonia |
| 6 | Luciano Boggio | River Plate |
| 6 | Pablo Silva | Villa Española |
| 6 | Hernan Rivero | Wanderers |
| 5 | Angel Cayetano | Cerro Largo |
| 5 | Nicolas Dibble | Plaza Colonia |
| 5 | Gustavo Alles | Progreso |
| 5 | Heber Gaston Colman | Progreso |
| 5 | Andrew Teuten | Torque |
| 4 | Ignacio Pereira | Fenix |
| 4 | Rodrigo Amaral | Fenix |
| 4 | Emiliano Garcia | Liverpool |
| 4 | Hernan Figueredo | Liverpool |
| 4 | Lucas Viatri | Maldonado |
| 4 | Alfonso Trezza | Nacional |
| 4 | Agustin Canobbio | Peñarol |
| 4 | Ariel Nahuelpan | Peñarol |
| 4 | Cristian Rodriguez | Plaza Colonia |
| 4 | Emilio Zeballos | Plaza Colonia |
| 4 | Emiliano Villar | Rentistas |
| 4 | Jorge Ramirez | Sud America |
| 4 | Gustavo del Prete | Torque |
| 4 | Juan Cejas | Torque |
| 4 | Dennis Olivera | Villa Española |
| 4 | Mauro Mendez | Wanderers |
| 4 | Nicolas Quagliata | Wanderers |
| 3 | Alan Rodriguez | Boston River |
| 3 | Enzo Larrosa | Boston River |
| 3 | Federico Rodriguez | Cerrito |
| 3 | Santiago Paiva | Cerro Largo |
| 3 | Luciano Nequecaur | Fenix |
| 3 | Gaston Martirena | Liverpool |
| 3 | Santiago Ramirez | Nacional |
| 3 | Jesus Trindade | Peñarol |
| 3 | Leandro Suhr | Plaza Colonia |
| 3 | Mario Risso | Plaza Colonia-Nacional |
| 3 | Lucas Morales | Progreso |
| 3 | Jonathan Urretaviscaya | Rentistas |
| 3 | Adrian Leites | River Plate |
| 3 | Gonzalo Castro | River Plate |
| 3 | Marcos Camarda | Sud America |
| 3 | Pablo Caballero | Sud America |
| 3 | Pablo Mouche | Sud America |
| 3 | Pablo Olivera | Sud America |
| 3 | Jose Alvarez | Torque |
| 3 | Marcelo Allende | Torque |
| 3 | Leonardo Pais | Wanderers |
| 3 | Rodrigo Rivero | Wanderers |
| 2 | Daniel Nicolas Gonzalez | Boston River |
| 2 | Jose Alberti | Boston River |
| 2 | Pedro Gaston Alvarez | Boston River |
| 2 | Maximiliano Perez | Cerrito |
| 2 | Yonatan Rodriguez | Cerrito |
| 2 | Augusto Max | Cerro Largo |
| 2 | Leandro Onetto | Cerro Largo |
| 2 | Mauro Brasil | Cerro Largo |
| 2 | Agustin Alfaro | Fenix |
| 2 | Gustavo Viera | Fenix |
| 2 | Jose Luis Rodriguez | Fenix |
| 2 | Juan Alvez | Fenix |
| 2 | Alan Medina | Liverpool |
| 2 | Thomas Chacon | Liverpool |
| 2 | Diego Casas | Maldonado |
| 2 | Facundo Batista | Maldonado |
| 2 | Leonardo Federico Ramos | Maldonado |
| 2 | Matias Aguirregaray | Maldonado |
| 2 | Washington Eduardo Darias | Maldonado |
| 2 | Brian Ocampo | Nacional |
| 2 | Camilo Candido | Nacional |
| 2 | Christian Almeida | Nacional |
| 2 | Matias Zunino | Nacional |
| 2 | Diego Gonzalo Vega | Nacional-Fenix |
| 2 | Alvaro Fernandez | Plaza Colonia |
| 2 | Gonzalo Camargo | Plaza Colonia |
| 2 | Juan Mascia | Plaza Colonia |
| 2 | Yvo Calleros | Plaza Colonia |
| 2 | Luciano Rodriguez | Progreso |
| 2 | Enzo Joaquin Sosa | Rentistas |
| 2 | Facundo Bonifazi | River Plate |
| 2 | Marcos Montiel | River Plate |
| 2 | Tiago Galletto | River Plate |
| 2 | Dario Pereira | Torque |
| 2 | Franco Catarozzi | Torque |
| 2 | Franco Pizzichillo | Torque |
| 2 | Hugo Diego Arismendi | Torque |
| 2 | Facundo Tancredi | Villa Española |
| 2 | Mathias Riquero | Villa Española |
| 2 | Santiago Lopez | Villa Española |
| 2 | Santiago Ramirez | Villa Española |
| 2 | Bruno Veglio | Wanderers |
| 2 | Diego Hernandez | Wanderers |
| 2 | Diego Riolfo | Wanderers |
| 2 | Ignacio Laquintana | Wanderers |
| 2 | Juan Aguirre | Wanderers |
| 2 | Mathias Abero | Wanderers |
| 1 | Agustin Nadruz | Boston River |
| 1 | Bruno Barja | Boston River |
| 1 | Fabian Agustin Davila | Boston River |
| 1 | Martin Fernandez | Boston River |
| 1 | Nicolas Freitas | Boston River |
| 1 | Cristian Cruz | Cerrito |
| 1 | Esteban da Silva | Cerrito |
| 1 | Flavio Scarone | Cerrito |
| 1 | Ignacio Aviles | Cerrito |
| 1 | Juan Ortiz | Cerrito |
| 1 | Matias Ferreira | Cerrito |
| 1 | Agustin Heredia | Cerro Largo |
| 1 | Briant D'Altoe | Cerro Largo |
| 1 | Emanuel Beltran | Cerro Largo |
| 1 | Ignacio Vazquez | Cerro Largo |
| 1 | Martin Bueno | Cerro Largo |
| 1 | Mauro Estol | Cerro Largo |
| 1 | Angel Rodriguez | Fenix |
| 1 | Edgardo Andres Schetino | Fenix |
| 1 | Edward Barboza | Fenix |
| 1 | Fabian Estotanoff | Fenix |
| 1 | Francisco Martirena | Fenix |
| 1 | Kaique | Fenix |
| 1 | Nicolas Ramos | Fenix |
| 1 | Fabricio Diaz | Liverpool |
| 1 | Mauricio Loffreda | Liverpool |
| 1 | Rodrigo Viega | Liverpool |
| 1 | Santiago Viera | Liverpool |
| 1 | Facundo Tealde | Maldonado |
| 1 | Guillermo Cotugno | Maldonado |
| 1 | Hernan Toledo | Maldonado |
| 1 | Joaquin Varela | Maldonado |
| 1 | Lucas Fernandez | Maldonado |
| 1 | Mariano Bogliacino | Maldonado |
| 1 | Pablo Lima | Maldonado |
| 1 | Rodrigo Muniz | Maldonado |
| 1 | Tomas Conechny | Maldonado |
| 1 | Andres D'Alessandro | Nacional |
| 1 | Armando Mendez | Nacional |
| 1 | Guillermo May | Nacional |
| 1 | Guzman Corujo | Nacional |
| 1 | Marcos Cantera | Nacional |
| 1 | Carlos Rodriguez | Peñarol |
| 1 | Gary Kagelmacher | Peñarol |
| 1 | Maximiliano Pereira | Peñarol |
| 1 | Walter Gargano | Peñarol |
| 1 | Haibrany Ruiz Diaz | Plaza Colonia |
| 1 | Leonai | Plaza Colonia |
| 1 | Alex Silva | Progreso |
| 1 | Bryan Bentaberry | Progreso |
| 1 | Fabricio Fernandez | Progreso |
| 1 | Jonathan Barboza | Progreso |
| 1 | Luciano Olaizola | Progreso |
| 1 | Pablo Martin Marta | Progreso |
| 1 | Ricardo Nahuel Roldan | Progreso |
| 1 | Rodrigo Mieres | Progreso |
| 1 | Andres Rodales | Rentistas |
| 1 | Franco Perez | Rentistas |
| 1 | Juninho Rocha | Rentistas |
| 1 | Mateo Baltasar Barcia | Rentistas |
| 1 | Nahuel Acosta | Rentistas |
| 1 | Tabare Viudez | Rentistas |
| 1 | Facundo Bone | River Plate |
| 1 | Horacio Salaberry | River Plate |
| 1 | Mauricio Affonso | River Plate |
| 1 | Nicolas Rodriguez | River Plate |
| 1 | Pablo Garcia | River Plate |
| 1 | Agustin Cayetano | Sud America |
| 1 | Alex Santeyano | Sud America |
| 1 | Bruno Gimenez | Sud America |
| 1 | Luis Morales | Sud America |
| 1 | Santiago Etchebarne | Sud America |
| 1 | Alejandro Peña | Torque |
| 1 | Alvaro Brun | Torque |
| 1 | Axel Perez | Torque |
| 1 | Gabriel Chocobar | Torque |
| 1 | Matias Cabrera | Torque |
| 1 | Cristhian Tizon | Villa Española |
| 1 | Facundo Godoy | Villa Española |
| 1 | Facundo Silva | Villa Española |
| 1 | Gabriel Albin | Villa Española |
| 1 | Jonathan Rios | Villa Española |
| 1 | Nicolas Digiano | Villa Española |
| 1 | Robert Flores | Villa Española |
| 1 | William Machado | Villa Española |
| 1 | Sebastian Blanco | Wanderers |
| Autogoles | ||
| Jugador | Equipo | |
| 2 | Santiago Brunelli | River Plate |
| 1 | Daniel Nicolas Gonzalez | Boston River |
| 1 | Leandro Lozano | Boston River |
| 1 | Ignacio Vazquez | Cerro Largo |
| 1 | Mauro Brasil | Cerro Largo |
| 1 | Rodrigo Amaral | Fenix |
| 1 | Adolfo Lima | Maldonado |
| 1 | Joaquin Varela | Maldonado |
| 1 | Armando Mendez | Nacional |
| 1 | Nicolas Marichal | Nacional |
| 1 | Nicolas Guirin | Plaza Colonia |
| 1 | Nicolas Olivera | Plaza Colonia |
| 1 | Bryan Bentaberry | Progreso |
| 1 | Danilo Asconeguy | Progreso |
| 1 | Pablo Martin Marta | Progreso |
| 1 | Robert Herrera | River Plate |
| 1 | Diego Lopez | Sud America |
| 1 | Emiliano Albin | Villa Española |
| 1 | Facundo Silva | Villa Española |
| 1 | Bruno Veglio | Wanderers |
| 1 | Hernan Rivero | Wanderers |
| 1 | Juan Izquierdo | Wanderers |