| COPA DE HOLANDA 2021-2022 | ||||
| 1º Ronda Preliminar | ||||
| 14-ago-2021 | Veghel | Blauw Geel '38 | 1 | Van der Zanden |
| Lisse | 2 | Tarani, Noordhoff | ||
| 14-ago-2021 | Hoorn | Hollandia | 1 | Deen |
| ACV | 5 | Quispel (2), Grevink, De Wit (A), Jagt | ||
| 14-ago-2021 | Haaksbergen | HSC'21 | 1(9) | Ottink |
| Excelsior '31 | 1(8) | Beverdam | ||
| 14-ago-2021 | Amsterdam | Ajax Amateurs | 2 | Bartels, Smal |
| EVV | 1 | Respen | ||
| 14-ago-2021 | Watergraafsmeer | JOS Watergraafsmeer | 1 | Huijman |
| Ter Leede | 5 | Marti (2), Stijn, Hoekstra, Autar | ||
| 14-ago-2021 | Beverwijk | DEM | 1(4) | Owusu-Ansah |
| Sparta Nijkerk | 1(5) | Van Groen | ||
| 2º Ronda Preliminar | ||||
| 21-sep-2021 | Veen | Achilles | 3 | Verstraaten, Van Huijgevoort, Sebregts |
| DTS Ede | 2 | Holtman, Palm | ||
| 21-sep-2021 | Amsterdam | Ajax Amsterdam | 4 | Van Aggele, Van der Slot (A), Moussa, De Jong |
| VVSB | 1 | Halman | ||
| 21-sep-2021 | Hendrik-Ido- | ASWH | 1 | Admiraal |
| Ambacht | H.V. & C.V. Quick | 0 | ||
| 21-sep-2021 | Barendrecht | Barendrecht | 3 | Monster, Bakour, Vorthoren |
| Scheveningen | 0 | |||
| 21-sep-2021 | Ermelo | DVS'33 | 2(4) | Kruisheer, Vloedgraven |
| Noordwijk | 2(2) | Bouwman, Wendt | ||
| 21-sep-2021 | Lisse | Lisse | 1 | Zwetsloot |
| AFC | 2 | De Mooij, Ignacio | ||
| 21-sep-2021 | Goes | GOES | 1 | Tiebosch (P) |
| DOVO | 2 | Achefay, Hak | ||
| 21-sep-2021 | Veenendaal | GVVV | 3 | Bitter, Yen Thije, Van de Haar |
| VVOG | 1 | Dijkhof | ||
| 21-sep-2021 | Hardenberg | HHC | 0 | |
| Ambacht | Capelle | 2 | Slabbekoorn, Van der Sande | |
| 21-sep-2021 | Hoek | Hoek | 2 | Schalwijk, Impens |
| SteDoCo | 3 | Verheul, Schroder, Hiwat | ||
| 21-sep-2021 | Spakenburg | Ijsselmeervogels | 3 | Tadmine, Poepon, Tekfaoui |
| Sportlust'46 | 1 | Verhagen | ||
| 21-sep-2021 | Heemskerk | ODIN'59 | 1 | Kooge |
| De Treffers | 2 | Maertzdorf, Zwanen | ||
| 21-sep-2021 | Katwijk | Quick Boys | 0 | |
| Rijnsburgse Boys | 2 | Zeldenrust, Van der Moot | ||
| 21-sep-2021 | Nijkerk | Sparta Nijkerk | 2 | Buitenhuis, Fransberg |
| Sliedrecht | 0 | |||
| 21-sep-2021 | Katwijk | VV Katwijk | 2 | El Azzouti, Freriks |
| Harkemase Boys | 3 | Esseboom (A), Bouius, Margaritha | ||
| 22-sep-2021 | Heemskerk | ADO'20 | 2 | Tesselaar, Mazreku |
| Koninklijke | 1 | Brandsma | ||
| 22-sep-2021 | Gemert | Gemert | 3 | Dekker (2), Daniels |
| TEC | 1 | Van Rijn | ||
| 22-sep-2021 | Gorinchem | GVV Unitas | 1 | Hak |
| Ter Leede | 0 | |||
| 22-sep-2021 | Utrecht | USV Hercules | 1(3) | Van Gorkom |
| ACV | 1(4) | Huser | ||
| 22-sep-2021 | Hoogland | Hhogland | 0 | |
| Westlandia | 1 | Memisoglu | ||
| 22-sep-2021 | Werkendam | Kozakken Boys | 2 | Stout, Lommers |
| Ambacht | RKSV Groene Ster | 0 | ||
| 22-sep-2021 | Amsterdam | OFC | 0 | |
| Excelsior Maasluis | 2 | Ouali (P), Ramos | ||
| 22-sep-2021 | Staphorst | Staphorst | 3 | Reuvers (3) |
| Dongen | 1 | Van Bree | ||
| 22-sep-2021 | Spakenburg | Spakenburg | 5 | Van der Linden, Eindhoven, Van Lopik, Schilder, Van Zundert (P) |
| UNA | 2 | Koc | ||
| 22-sep-2021 | Oss | OSS'20 | 2 | Peltzer, Pijnenburg |
| HSC | 1 | Van der Weide | ||
| 1º Ronda | ||||
| 26-oct-2021 | Hoornaar | SteDoCo | 0 | |
| Utrecht | 5 | Balk, Boussaid, Maher, Sylla, Van de Streek | ||
| 26-oct-2021 | Assen | ACV | 0 | |
| Maastricht | 3 | Remans (3) | ||
| 26-oct-2021 | Hendrik-Ido- | ASWH | 1 | Admiraal |
| Ambacht | Heracles Almelo | 3 | Vloet (2), Verhoeve | |
| 26-oct-2021 | Ermelo | DVS'33 | 2 | Roemeon (2) |
| Eindhoven | 1 | Dahlhaus | ||
| 26-oct-2021 | Werkendam | Kozakken Boys | 1 | Van Ingen |
| Telstar | 2 | Plet (P), Overtoom | ||
| 26-oct-2021 | Volendam | Volendam | 0 | |
| Emmen | 3 | Mendes (2), Assehnoun | ||
| 26-oct-2021 | Nijkerk | Sparta Nijkerk | 0 | |
| ADO den Haag | 2 | Verheydt, Rottier | ||
| 26-oct-2021 | Zwolle | PEC | 4 | Nakayama, Saymak, Huiberts, Fernandes |
| De Graafschap | 1 | Konings (P) | ||
| 26-oct-2021 | Kerkrade | Roda | 2 | Livramento, Vente |
| Ambacht | Den Bosch | 1 | Kuijpers | |
| 26-oct-2021 | Spakenburg | Spakenburg | 3 | Junte, Zeeman, Schilder |
| Dordrecht | 0 | |||
| 26-oct-2021 | Breda | NAC | 1(4) | Haye |
| Venlo | 1(2) | Leliendal | ||
| 27-oct-2021 | Oss | OSS'20 | 0 | |
| Twente | 2 | Zerrouki, Van Wolfswinkel (P) | ||
| 27-oct-2021 | Veen | Achilles Veen | 4 | Koenen (2), Sebregts, Geeroms |
| GVV Unitas | 0 | |||
| 27-oct-2021 | Heemskerk | ADO'20 | 2 | Brenna (2) |
| Barendrecht | 3 | Van Dijk, Husen, Jongman | ||
| 27-oct-2021 | Amsterdam | AFC | 1 | Maatsen |
| Heerenveen | 2 | Veerman, Stevanovic | ||
| 27-oct-2021 | Almere | Almere City | 0 | |
| Go Ahead Eagles | 2 | Brouwers (P), Cordoba | ||
| 27-oct-2021 | Capelle aan den | Capelle | 0 | |
| Ijssel | NEC | 3 | Tavsan (2), Romeny | |
| 27-oct-2021 | Groesbeek | De Treffers | 2(6) | Ten Den, Janssen |
| Rijnsburgse Boys | 2(5) | Artien, Zeldenrust | ||
| 27-oct-2021 | Sittard | Fortuna | 3 | Seuntjens, Cox (2) |
| TOP Oss | 0 | |||
| 27-oct-2021 | Veenendaal | GVVV | 0 | |
| Sparta | 2 | Engels, Van Crooij | ||
| 27-oct-2021 | Harkema | Harkemase Boys | 2 | Visser, Bentum |
| Ambacht | DOVO | 1 | Van Nispen | |
| 27-oct-2021 | Spakenburg | Ijsselmeervogels | 0 | |
| Excelsior | 3 | Botermans (2), Niemeijer | ||
| 27-oct-2021 | Staphorst | Staphorst | 0 | |
| Gemert | 3 | Van de Broek, Kemper, Van Loon | ||
| 27-oct-2021 | Naaldwijk | Westlandia | 2 | Bransen, Van Ree |
| Excelsior Maasluis | 5 | Urbanus (2, 1P), El Baad, Heuvelman, Muis | ||
| 27-oct-2021 | Groningen | Groningen | 4 | Postema (2), Irandust, Strand Larsen |
| Helmond Sport | 0 | |||
| 28-oct-2021 | Duivendrecht | Ajax Amateurs | 0 | |
| Cambuur | 5 | Flemming (A), Kraslev, Schouten, Smal (A), Doodeman | ||
| 28-oct-2021 | Waalwijk | Waalwijk | 3 | Bel Hassani, Stokkens, Bakari |
| Willem II | 0 | |||
| 2º Ronda | ||||
| 14-dic-2021 | Den Haag | ADO Den Haag | 4 | Elia, Seedorf, Verheydt (2) |
| Gemert | 2 | Den Dekker (2) | ||
| 14-dic-2021 | Zwolle | PEC | 4 | Voet, Van den Berg, Adzic, Tedic |
| Maastricht | 0 | Remans (3) | ||
| 14-dic-2021 | Emmen | Emmen | 0 | |
| Excelsior Maasluis | 1 | Wennekers | ||
| 14-dic-2021 | Breda | NAC | 3 | Haye (2), Kotzebue |
| Utrecht | 2 | Van der Hoorn, Douvikas | ||
| 14-dic-2021 | Velsen-Zuid | Telstar | 5 | Zakir, Van Velzen, Blackson, Molenaar, Fernandes |
| SV Spakenburg | 3 | Van der Linden (2), Van Zundert | ||
| 15-dic-2021 | Alkmaar | AZ | 4 | Pavlidis, Karlsson (2), Barasi |
| Heracles Almelo | 1 | Basacikoglu | ||
| 15-dic-2021 | Enschede | Twente | 2 | Troupee, Ugalde |
| Feyenoord | 1 | Dessers | ||
| 15-dic-2021 | Harkema | Harkemase Boys | 0 | |
| Waalwijk | 5 | Oukili, Stokkers (2), Lutonda, Bakari | ||
| 15-dic-2021 | Arnhem | Vitesse | 2 | Frederiksen (2) |
| Ambacht | Sparta | 1 | Van Crooij (P) | |
| 15-dic-2021 | Rotterdam | Excelsior | 2 | Niemeijer, Baas |
| Groningen | 4 | Ngonge, El Hankouri (P), Strand Larsen (2) | ||
| 15-dic-2021 | Amsterdam | Ajax | 4 | Taylor, Danilo (2, 1P), Hlynsson (P) |
| Barendrecht | 0 | |||
| 15-dic-2021 | Deventer | Go Ahead Eagles | 2 | Lidberg (2) |
| Roda | 0 | |||
| 15-dic-2021 | Eindhoven | PSV | 2 | Doan (2) |
| Fortuna Sittard | 0 | |||
| 16-dic-2021 | Leeuwarden | Cambuur | 1 | Hendriks |
| NEC | 2 | Gullit (A), Proper | ||
| 16-dic-2021 | Veen | Achilles Veen | 0 | |
| DVS'33 Ermelo | 2 | Van Hilten, Akla | ||
| 16-dic-2021 | Heerenveen | Heerenveen | 2 | De Jong, Veerman |
| De Treffers | 0 | |||
| Octavos de Final | ||||
| 18-ene-2022 | Waalwijk | Waalwijk | 4 | Kuijpers, Odgaard (3) |
| ADO den Haag | 2 | El Maach (A), Verheydt | ||
| 18-ene-2022 | Arnhem | Vitesse | 2 | Huisman, Openda |
| DVS'33 | 0 | |||
| 18-ene-2022 | Heerenveen | Heerenveen | 0 | |
| Go Ahead Eagles | 1 | Cordoba | ||
| 19-ene-2022 | Groningen | Groningen | 1 | De Leeuw |
| NEC | 2 | Vedonk, Duelund | ||
| 19-ene-2022 | Breda | NAC | 2 | Bannis, De Rooij |
| PEC | 1 | Saymak | ||
| 19-ene-2022 | Enschede | Twente | 1 | Van Wolfswinkel (P) |
| AZ | 2 | Pleguezuelo (A), Pavlidis | ||
| 20-ene-2022 | Eindhoven | PSV | 2 | Bruma, Veerman |
| Telstar | 1 | Aktas | ||
| 20-ene-2022 | Amsterdam | Ajax | 9 | Tagliafico, Danilo (4, 1P), Regeer, Hlynsson, Daramy (2) |
| Excelsior Maasluis | 0 | |||
| Cuartos de Final | ||||
| 8-feb-2022 | Eindhoven | PSV | 4 | Madueke, Gotze (2), Gakpo |
| NAC | 0 | |||
| 9-feb-2022 | Waalwijk | Waalwijk | 0 | |
| AZ | 4 | De Wit, Pavlidis, Karlsson (P), Aboukhlal | ||
| 9-feb-2022 | Amsterdam | Ajax | 5 | Antony (2), Haller (2), Tadic |
| Vitesse | 0 | |||
| 10-feb-2022 | Nijmegen | NEC | 0 | |
| Go Ahead Eagles | 2 | Brouwers (P), Botos | ||
| Semifinales | ||||
| 2-mar-2022 | Deventer | Go Ahead Eagles | 1 | Cordoba |
| PSV | 2 | Zahavi, Veerman | ||
| 3-mar-2022 | Alkmaar | AZ | 0 | |
| Ajax | 2 | Berghuis, Klaassen | ||
| FINAL | ||||
| 17-abr-2022 | Eindhoven | PSV | 2 | Gutierrez, Gakpo |
| Ajax | 1 | Gravenberch | ||