| GOLEADORES CAMPEONATO APERTURA 2025 | |||
| Goles | Jugador | Equipo | |
| 3 | Juan Iturbe | Cerro Porteño | |
| 3 | Fernando Fernandez | Guarani | |
| 3 | Lorenzo Melgarejo | Libertad | |
| 3 | Wilfrido Baez | Recoleta | |
| 2 | Jonathan Torres | Cerro Porteño | |
| 2 | Oscar Cardozo | Libertad | |
| 2 | Roque Santa Cruz | Libertad | |
| 2 | Ruben Lezcano | Libertad | |
| 2 | Derlis Gonzalez | Olimpia | |
| 2 | Rodney Redes | Olimpia | |
| 2 | Cristhian Ocampos | Sportivo Ameliano | |
| 2 | Luis Ortiz | Sportivo Ameliano | |
| 2 | Juan Manuel Romero | Sportivo Trinidense | |
| 1 | Pedro Sosa | 2 de Mayo | |
| 1 | Ronald Cornet | 2 de Mayo | |
| 1 | Sergio Bareiro | 2 de Mayo | |
| 1 | Cecilio Dominguez | Cerro Porteño | |
| 1 | Clementino Gonzalez | General Caballero | |
| 1 | Juan Alexander Franco | General Caballero | |
| 1 | Ronald Roa | General Caballero | |
| 1 | Teodoro Sebastian Arce | General Caballero | |
| 1 | Daniel Perez | Guarani | |
| 1 | William Mendieta | Guarani | |
| 1 | Hugo Martinez | Libertad | |
| 1 | Ivan Franco | Libertad | |
| 1 | Gustavo Caballero | Nacional | |
| 1 | Hugo Fernandez | Olimpia | |
| 1 | Javier Dominguez | Olimpia | |
| 1 | Hugo Sandoval | Recoleta | |
| 1 | Lucas Gonzalez | Recoleta | |
| 1 | Fredy Vera | Sportivo Ameliano | |
| 1 | Elvio Vera | Sportivo Luqueño | |
| 1 | Rodrigo Alborno | Sportivo Luqueño | |
| 1 | Luis de la Cruz | Sportivo Trinidense | |
| 1 | Nelson Ariel Gauto | Sportivo Trinidense | |
| 1 | Ronaldo Baez | Sportivo Trinidense | |
| 1 | Alan Paredes | Tembetary | |
| 1 | Estiven Omar Perez | Tembetary | |
| 1 | Jorge Nuñez | Tembetary | |
| 1 | Willian Candia | Tembetary | |
| Autogoles | |||
| Jugador | Equipo | ||
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