| GOLEADORES CAMPEONATO APERTURA 2022 | ||
| Goles | Jugador | Equipo |
| 16 | Nicolas Ibañez | Pachuca |
| 13 | Henry Martin | America |
| 10 | Andre-Pierre Gignac | Tigres |
| 9 | Martin Barragan | Puebla |
| 9 | Camilo Sanvezzo | Toluca |
| 8 | Lucas di Yorio | Leon |
| 8 | Abel Hernandez | San Luis |
| 8 | Jean Meneses | Toluca |
| 7 | Alejandro Zendejas | America |
| 7 | Facundo Batista | Necaxa |
| 7 | Harold Preciado | Santos |
| 6 | Jonathan Rodriguez | America |
| 6 | Gabriel Fernandez | Juarez |
| 6 | German Berterame | Monterrey |
| 6 | Juan Dinenno | Pumas |
| 6 | Javier Correa | Santos |
| 6 | Leandro Suarez | Santos |
| 6 | Leonardo Fernandez | Toluca |
| 5 | Diego Valdes | America |
| 5 | Julian Quiñones | Atlas |
| 5 | Santiago Gimenez | Cruz Azul |
| 5 | Jesus Gallardo | Monterrey |
| 5 | Rodrigo Aguirre | Monterrey |
| 5 | Rogerio Funes Mori | Monterrey |
| 5 | Jordi Cortizo | Puebla |
| 5 | Eduardo Salvio | Pumas |
| 5 | Fernando Gorriaran | Santos |
| 4 | Angel Zaldivar | Guadalajara |
| 4 | Alan Medina | Juarez |
| 4 | Victor Davila | Leon |
| 4 | Arturo Gonzalez | Monterrey |
| 4 | Milton Gimenez | Necaxa |
| 4 | Aviles Hurtado | Pachuca |
| 4 | Romario Ibarra | Pachuca |
| 4 | Diogo | Pumas |
| 4 | Angel Sepulveda | Queretaro |
| 4 | Ariel Nahuelpan | Queretaro |
| 4 | Eduardo Aguirre | Santos |
| 4 | Juan Francisco Brunetta | Santos |
| 4 | Francisco Sebastian Cordova | Tigres |
| 4 | Lucas Rodriguez | Tijuana |
| 3 | Alvaro Fidalgo | America |
| 3 | Federico Viñas | America |
| 3 | Roger Martinez | America |
| 3 | Jonathan Ozziel Herrera | Atlas |
| 3 | Gonzalo Carneiro | Cruz Azul |
| 3 | Michael Estrada | Cruz Azul |
| 3 | Ernesto Alexis Vega | Guadalajara |
| 3 | Eduard Bello | Mazatlan |
| 3 | Nicolas Benedetti | Mazatlan |
| 3 | Gustavo Cabral | Pachuca |
| 3 | Illian Hernandez | Pachuca |
| 3 | Javier Lopez | Pachuca |
| 3 | Israel Reyes | Puebla |
| 3 | Florian Thauvin | Tigres |
| 3 | Carlos Gonzalez | Toluca |
| 2 | Brian Rodriguez | America |
| 2 | Emilio Lara | America |
| 2 | Richard Sanchez | America |
| 2 | Angel Romero | Cruz Azul |
| 2 | Carlos Rotondi | Cruz Azul |
| 2 | Carlos Uriel Antuna | Cruz Azul |
| 2 | Christian Alejandro Tabo | Cruz Azul |
| 2 | Jose Ignacio Rivero | Cruz Azul |
| 2 | Rodrigo Huescas | Cruz Azul |
| 2 | Carlos Cisneros | Guadalajara |
| 2 | Roberto Alvarado | Guadalajara |
| 2 | Jesus Dueñas | Juarez |
| 2 | Federico Martinez | Leon |
| 2 | Yairo Moreno | Leon |
| 2 | Emilio Sanchez | Mazatlan |
| 2 | Oswaldo Alanis | Mazatlan |
| 2 | John Steven Medina | Monterrey |
| 2 | Luis Romo | Monterrey |
| 2 | Bryan Garnica | Necaxa |
| 2 | Erick Sanchez | Pachuca |
| 2 | Israel Luna | Pachuca |
| 2 | Luis Chavez | Pachuca |
| 2 | Paulino | Pachuca |
| 2 | Victor Guzman | Pachuca |
| 2 | Gustavo Ferrareis | Puebla |
| 2 | Josy Altidore | Puebla |
| 2 | Maximiliano Araujo | Puebla |
| 2 | Omar Fernandez | Puebla |
| 2 | Ettson Ayon | Queretaro |
| 2 | Felix Torres | Santos |
| 2 | Hugo Rodriguez | Santos |
| 2 | Juan Pablo Vigon | Tigres |
| 2 | Samir | Tigres |
| 2 | Alex Renato Ibarra | Tijuana |
| 2 | Edgar Lopez | Tijuana |
| 2 | Franco di Santo | Tijuana |
| 2 | Lisandro Lopez | Tijuana |
| 2 | Andres Mosquera | Toluca |
| 2 | Fernando Navarro | Toluca |
| 2 | Jordan Sierra | Toluca |
| 2 | Marcel Ruiz | Toluca |
| 2 | Valber Huerta | Toluca |
| 1 | Jonathan dos Santos | America |
| 1 | Miguel Layun | America |
| 1 | Salvador Reyes | America |
| 1 | Sebastian Caceres | America |
| 1 | Aldo Rocha | Atlas |
| 1 | Angel Jeremy Marquez | Atlas |
| 1 | Christopher Trejo | Atlas |
| 1 | Gaddi Aguirre | Atlas |
| 1 | Hugo Nervo | Atlas |
| 1 | Jesus Ocejo | Atlas |
| 1 | Julio Furch | Atlas |
| 1 | Luis Reyes | Atlas |
| 1 | Ivan Morales | Cruz Azul |
| 1 | Jesus Alonzo Escoboza | Cruz Azul |
| 1 | Jose Ramiro Mori | Cruz Azul |
| 1 | Rafael Baca | Cruz Azul |
| 1 | Cristian Calderon | Guadalajara |
| 1 | Fernando Beltran | Guadalajara |
| 1 | Jesus Orozco | Guadalajara |
| 1 | Jose Gonzalez | Guadalajara |
| 1 | Luis Olivas | Guadalajara |
| 1 | Santiago Ormeño | Guadalajara |
| 1 | Sebastian Perez Bouquet | Guadalajara |
| 1 | Sergio Flores | Guadalajara |
| 1 | Ariel Matias Garcia | Juarez |
| 1 | Carlos Fierro | Juarez |
| 1 | Dario Lezcano | Juarez |
| 1 | Darwin Machis | Juarez |
| 1 | Maximiliano Olivera | Juarez |
| 1 | Angel Mena | Leon |
| 1 | Byron Castillo | Leon |
| 1 | Fidel Ambriz | Leon |
| 1 | Joel Campbell | Leon |
| 1 | Jose Alfonso Alvarado | Leon |
| 1 | Osvaldo Rodriguez | Leon |
| 1 | Paul Bellon | Leon |
| 1 | Bryan Colula | Mazatlan |
| 1 | Gabriel Lopez | Mazatlan |
| 1 | Gonzalo Sosa | Mazatlan |
| 1 | Miguel Sansores | Mazatlan |
| 1 | Roberto Meraz | Mazatlan |
| 1 | Hector Moreno | Monterrey |
| 1 | Jaziel Martinez | Monterrey |
| 1 | Maximiliano Meza | Monterrey |
| 1 | Sebastian Vegas | Monterrey |
| 1 | Agustin Oliveros | Necaxa |
| 1 | Alexis Peña | Necaxa |
| 1 | Brian Garcia | Necaxa |
| 1 | Fabricio Formiliano | Necaxa |
| 1 | Fernando Madrigal | Necaxa |
| 1 | Mauricio Isais | Pachuca |
| 1 | Amaury Escoto | Puebla |
| 1 | Francisco Aristeguieta | Puebla |
| 1 | Adrian Aldrete | Pumas |
| 1 | Gustavo del Prete | Pumas |
| 1 | Jeronimo Rodriguez | Pumas |
| 1 | Jorge Ruvalcaba | Pumas |
| 1 | Julio Gonzalez | Pumas |
| 1 | Nicolas Freire | Pumas |
| 1 | Clifford Aboagye | Queretaro |
| 1 | Jordan Silva | Queretaro |
| 1 | Jose Angulo | Queretaro |
| 1 | Juan Romagnoli | Queretaro |
| 1 | Mario Osuna | Queretaro |
| 1 | Pablo Barrera | Queretaro |
| 1 | Raul Torres | Queretaro |
| 1 | Facundo Waller | San Luis |
| 1 | John Murillo | San Luis |
| 1 | Rubens Sanhueza | San Luis |
| 1 | Sabin Moreno | San Luis |
| 1 | Zahid Muñoz | San Luis |
| 1 | Brian Lozano | Santos |
| 1 | Carlos Acevedo | Santos |
| 1 | Carlos Emilio Orrantia | Santos |
| 1 | Diego Medina | Santos |
| 1 | Jose Lozano | Santos |
| 1 | Omar Campos | Santos |
| 1 | Guido Pizarro | Tigres |
| 1 | Jordy Caicedo | Tigres |
| 1 | Luis Quiñones | Tigres |
| 1 | Nicolas Lopez | Tigres |
| 1 | Raymundo Fulgencio | Tigres |
| 1 | Alexis Canelo | Tijuana |
| 1 | Federico Lertora | Tijuana |
| 1 | Joaquin Montecinos | Tijuana |
| 1 | Victor Guzman | Tijuana |
| 1 | Daniel Alvarez | Toluca |
| 1 | Jorge Torres | Toluca |
| 1 | Oscar Haret Ortega | Toluca |
| 1 | Raul Lopez | Toluca |
| 1 | Tiago Volpi | Toluca |
| Autogoles | ||
| Jugador | Equipo | |
| 2 | Milton Gimenez | Necaxa |
| 2 | Nicolas Freire | Pumas |
| 1 | Diego Valdes | America |
| 1 | Anderson Santamaria | Atlas |
| 1 | Jose Ramiro Mori | Cruz Azul |
| 1 | Rodrigo Huescas | Cruz Azul |
| 1 | Byron Castillo | Leon |
| 1 | Jaime Barreiro | Leon |
| 1 | Rodolfo Cota | Leon |
| 1 | Carlos Vargas | Mazatlan |
| 1 | Gil Alcala | Pumas |
| 1 | Hugo Rodriguez | Santos |
| 1 | Igor Lichnovsky | Tigres |
| 1 | Samir | Tigres |