| GOLEADORES CAMPEONATO DE 2ª DIVISION 2022 | |||
| Goles | Jugador | Equipo | |
| 8 | Bairon Monroy | San Marcos | |
| 6 | Diego Vallejos | Independiente | |
| 6 | Leandro Ruiz | Real San Joaquin | |
| 5 | Matias Villablanca | General Velasquez | |
| 5 | Ignacio Pinilla | Iberia | |
| 5 | Diego Cuellar | Lautaro | |
| 5 | Nahuel Donadell | San Marcos | |
| 4 | Alvaro Lopez | General Velasquez | |
| 4 | Jose Luis Silva | Lautaro | |
| 4 | Hernan Ramirez | Limache | |
| 4 | Augustine Ezeali | Rodelindo Roman | |
| 4 | Xabier Santos | Valdivia | |
| 3 | Alexander Bolaños | Concepcion | |
| 3 | Cristobal Vargas | Concepcion | |
| 3 | Kevin Serrano | General Velasquez | |
| 3 | Hugo Toro | Limache | |
| 3 | Nicolas Barrera | Real San Joaquin | |
| 3 | David Quiroz | Rodelindo Roman | |
| 3 | Nicolas Silva | Rodelindo Roman | |
| 3 | Gonzalo Aban | San Antonio | |
| 3 | Luciano Diaz | San Antonio | |
| 3 | Sergio Riffo | San Antonio | |
| 3 | Cristian Valenzuela | San Marcos | |
| 3 | Bastian Araya | Trasandino | |
| 3 | Joaquin Llanos | Trasandino | |
| 3 | Cristian Gonzalez | Valdivia | |
| 2 | Gabriel Vargas | Concepcion | |
| 2 | Ignacio Sepulveda | Concepcion | |
| 2 | Juan Sebastian Ibarra | Concepcion | |
| 2 | Lautaro Rigazzi | Concepcion | |
| 2 | Hugo Herrera | General Velasquez | |
| 2 | Tomas Pino | General Velasquez | |
| 2 | Erick Millalen | Iberia | |
| 2 | Luis Oyarzo | Iberia | |
| 2 | Javier Guzman | Independiente | |
| 2 | Nicolas Solabarrieta | Lautaro | |
| 2 | Rene Melendez | Lautaro | |
| 2 | Abel Herrera | Limache | |
| 2 | Nicolas Muñoz | Limache | |
| 2 | Kevin Campillay | Real San Joaquin | |
| 2 | Alessandro Rizzoli | Rodelindo Roman | |
| 2 | Luis Salazar | Rodelindo Roman | |
| 2 | Brian Leiva | San Antonio | |
| 2 | Flavio Rojas | San Antonio | |
| 2 | Rodrigo Auzmendi | San Marcos | |
| 2 | Alberto Hernandez | Trasandino | |
| 2 | Jose Tomas Arancibia | Trasandino | |
| 2 | Lucas Simon | Trasandino | |
| 2 | Wilson Martinez | Trasandino | |
| 2 | Carlos Pavez | Valdivia | |
| 2 | Emiliano Bonfigli | Valdivia | |
| 2 | Guillermo Avello | Valdivia | |
| 2 | Nicolas Astete | Valdivia | |
| 1 | Cristofer Salas | Concepcion | |
| 1 | Fabian Ramirez | Concepcion | |
| 1 | Daud Gazale | General Velasquez | |
| 1 | Diego Salas | General Velasquez | |
| 1 | Hernan Astudillo | General Velasquez | |
| 1 | John Alegria | General Velasquez | |
| 1 | Jorge Uribe | General Velasquez | |
| 1 | Juan Tobar | General Velasquez | |
| 1 | Patricio Troncoso | General Velasquez | |
| 1 | Ignacio Contreras | Iberia | |
| 1 | Marcelo Flores | Iberia | |
| 1 | Miguel Orellana | Iberia | |
| 1 | Alex Diaz | Independiente | |
| 1 | Felipe Escobar | Independiente | |
| 1 | Luciano Araya | Independiente | |
| 1 | Matias Pinto | Independiente | |
| 1 | Carlos Toselli | Lautaro | |
| 1 | Kevin Hidalgo | Lautaro | |
| 1 | Misael Llanten | Lautaro | |
| 1 | Nicolas Gutierrez | Lautaro | |
| 1 | Benjamin Inostroza | Limache | |
| 1 | Cristian Collao | Limache | |
| 1 | Diego Guillermo Huerta | Limache | |
| 1 | Raul Bernal | Limache | |
| 1 | Sebastian Romero | Limache | |
| 1 | Alejandro Quiero | Real San Joaquin | |
| 1 | Diego Figueroa | Real San Joaquin | |
| 1 | Luciano Meneses | Real San Joaquin | |
| 1 | Marcelo Carvajal | Real San Joaquin | |
| 1 | Nicolas Guerra | Real San Joaquin | |
| 1 | Santiago Salaberry | Real San Joaquin | |
| 1 | Fabian Bustos | Rodelindo Roman | |
| 1 | Jorge Lagues | Rodelindo Roman | |
| 1 | Nicolas Aravena | Rodelindo Roman | |
| 1 | Ramiro Galvez | Rodelindo Roman | |
| 1 | Junio Lopes | San Antonio | |
| 1 | Rodrigo Gattas | San Antonio | |
| 1 | Diego Ceron | San Marcos | |
| 1 | Felipe Baez | San Marcos | |
| 1 | Ignacio Mesias | San Marcos | |
| 1 | Mauricio Arias | San Marcos | |
| 1 | Mirko Serrano | San Marcos | |
| 1 | Valentin Coria | San Marcos | |
| 1 | Alejandro Rios | Trasandino | |
| 1 | Alejandro Zuñiga | Trasandino | |
| 1 | Douglas Estay | Trasandino | |
| 1 | Fabrizio Tomarelli | Trasandino | |
| 1 | Antoniop Estrada | Valdivia | |
| 1 | John Jorquera | Valdivia | |
| 1 | Renato Araya | Valdivia | |
| Autogoles | |||
| 1 | Cegy Duran | Trasandino | |
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